(Robert Glatter, MD, Forbes) New data from researchers at the University of Copenhagen provides stronger evidence linking certain bacteria that populate our intestinal tract with a higher risk for developing insulin resistance, ultimately a precursor to developing diabetes.
The research [suggests] that the gut microbiome might be a potential target for therapeutic intervention in this ravaging disease…
Those persons … whom we describe as insulin resistant–had elevated blood concentrations of a subgroup of amino acids known as branched-chain amino acids (BCAAs). But the key was this: The rise of the concentration of BCAAs levels in the bloodstream was ultimately related to specific changes in the gut bacterial composition and corresponding function.
Based on microbiologic data, the researchers determined that two bacteria species—Prevotella copri and Bacteroides vulgatus—were responsible for the bulk of gut BCAAs that were produced. But to see if gut bacteria were the actual cause of insulin resistance, the researchers fed mice with thePrevotella copri bacteria for 3 weeks. Compared to mice without the bacteria, the Prevotella copri-fed mice developed increased blood levels of BCAAs, insulin resistance and intolerance to glucose.[Click the title, above, to post a comment.]