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Embryonic Gene Reverses Aging in Adult Stem Cells

(University at Buffalo) The fountain of youth may reside in an embryonic stem cell gene named Nanog.
In a series of experiments at the University at Buffalo, the gene kicked into action dormant cellular processes that are key to preventing weak bones, clogged arteries and other telltale signs of growing old…
"Not only does Nanog have the capacity to delay aging, it has the potential in some cases to reverse it," says [Stelios T. Andreadis, PhD], noting that the embryonic stem cell gene worked in three different models of aging: cells isolated from aged donors, cells aged in culture, and cells isolated from patients with Hutchinson-Gilford progeria syndrome.
Additionally, the researchers showed that Nanog activated the central regulator of muscle formation, serum response factor (SRF), suggesting that the same results may be applicable for skeletal, cardiac and other muscle types.
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