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Controlling cardiac scarring could help heart tissue regenerate

(Virginia Tech) Literal heartbreak, from illness or injury, triggers the body's natural healing mechanisms. The result of such mending is often a scar. It's a patch that works, but fibrotic scar tissue replaces healthy heart muscle, a problem that has led scientists across the world to ponder ways to modify the wound-healing process for the benefit of patients.
An international team of researchers from the Virginia Tech Carilion Research Institute and the Universities of Frankfurt and Freiburg in Germany recently published a review paper online in Nature Reviews Drug Discovery -- one of the highest ranked journals in medical research -- that summarizes the potential therapeutic promise of targeting the non-muscle cells in the heart responsible for cardiac scarring.
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