A community for people who want to remain as healthy as possible as we age.

Researchers Identify Liver Pathway Linked to Negative Impacts of High-Fat, High-Cholesterol Diet

(University of Michigan) It's no secret that a high-fat, high-cholesterol "junk food" diet has been linked to major health problems, including high blood cholesterol and the buildup of plaques in the arteries, known as atherosclerosis.
Research led by the University of Michigan Life Sciences Institute has identified a pathway in the liver, controlled by a protein known as BAF60a, that contributes to these negative effects by stimulating the production of bile -- which helps the body to absorb more cholesterol and other fats from the foods we eat…
From an evolutionary perspective, it makes sense that our ancestors' bodies would want to kick into high gear to take full advantage of a rare source of fat, said Zhuo-Xian Meng, the study's lead author and a research investigator in Lin's lab.
"But now the environment has changed, fatty foods are everywhere and this adaptive response becomes maladaptive," Meng said.
[Click the title, above, to post a comment.]

0 comments:

Post a Comment

Please do not give advice. We can best help each other by telling what works for us, not what we think someone else should do.