(MedPage Today) The newer agents -- FDA approved and not approved -- can all be considered for the prevention of stroke in patients with nonvalvular atrial fibrillation, a science advisory from the American Heart Association/American Stroke Association stated.
(MedPage Today) A signaling factor that promotes blood vessel growth may play a role in the cerebral microbleeds that often follow an ischemic stroke, researchers reported. In a small prospective study, serum levels of vascular endothelial growth factor (VEGF) were elevated among stroke patients who had microbleeds, according to Pooja Dassan, MD.
(MedPage Today) The bright white spots that show up on brain MRIs in older people may be a manifestation of disease and not just a benign byproduct of aging.
(American Heart Association) Stroke patients receive faster treatment when emergency medical services (EMS) personnel notify hospitals a possible stroke patient is en route. However, emergency personnel fail to alert hospitals of incoming stroke patients in nearly one-third of cases. Researchers say improved stroke care systems can address geographical and other factors affecting EMS pre-notification.
(Science Daily) According to the American Stroke Association, the Food and Drug Administration-approved tPA (tissue plasminogen activator) is the best treatment for stroke caused by a blocked artery, but to be effective, it must be administered within three hours after symptoms start. If given outside that three-hour window, tPA has shown serious side effects in animal and human brains, including bleeding and breakdown of the brain's protective barrier… [But a combination of tPA and 3K3A-APC] reduced brain damage by more than half, eliminated tPA-induced bleeding and significantly improved motor ability.
(MedPage Today) Low-molecular weight heparin may help prevent early neurologic deterioration in patients with acute large artery stroke, researchers reported. In a post hoc analysis of a randomized controlled trial, patients given heparin instead of aspirin were significantly less likely to have neurologic deterioration within the first 10 days after stroke.
(MedPage Today) The FDA has issued 510(k) marketing approval for a clot removal device for treating patients experiencing acute ischemic stroke, device maker Stryker announced Monday. The Trevo Pro Retrieval System performed better than Merci Retrieval, made by Concentric Medical, now part of Stryker, in getting blood flowing back to the brain, according to a company news release.
(Science Daily) [S]cientists report that a therapy combining exercise with the neurovascular protective agent S-nitrosoglutathione (GSNO) improved recovery from stroke in a rat model. GSNO is a compound found naturally in the body and it has no known side effects or toxicity.
(MedPage Today) Stroke survivors are at an increased risk of post-traumatic stress disorder, which in turn puts them at risk of poor medication adherence, researchers found.
(MedPage Today) Blood pressure control is poor following an intracerebral hemorrhage (ICH), particularly among black patients longer term, researchers found.
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