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More Recent Research on Cancer

(Reuters) Young men who had smoked marijuana recreationally were twice as likely to be diagnosed with testicular cancer than men who have never used marijuana, according to a U.S. study.
(MyHealthNewsDaily) Some drugs that treat high blood pressure may increase the risk of lip cancer, a new study suggests. In the study, people who took the high blood pressure drug hydrochlorothiazide for five years or more were four times more likely to develop lip cancer, compared with those who did not take the drug.
(Science Daily) There has been an increase in the number of non-smokers being diagnosed with non-small cell lung cancer, according to new findings… Little is known about risk factors that can cause lung cancer in non-smokers, although recently the World Health Organization (WHO) confirmed earlier this year that exhaust fumes from diesel engines were a cause of lung cancer.
(Reuters Health) There is no evidence that getting screened for ovarian cancer helps women beat the dread disease, according to updated recommendations from a U.S. government-backed expert panel.
Community: Dr. Weil lists the “8 Signs of Ovarian Cancer”.
(Science Daily) Johns Hopkins researchers have created a synthetic protein that, when activated by ultraviolet light, can guide doctors to places within the body where cancer, arthritis and other serious medical disorders can be detected… The synthetic protein … does not zero in directly on the diseased cells. Instead, it binds to nearby collagen that has been degraded by various health disorders.
More . . .

(MedPage Today) A novel nanotechnology drug delivery system under development to infiltrate breast cancer tumors could pave the way for treating other diseases… The next generation of cancer-fighting drugs specifically target cancer proteins rather than attack cancer and noncancer cells indiscriminately.
(NIH News) Scientists have known for decades that cancer cells use more glucose than healthy cells, feeding the growth of some types of tumors. Now, a team … has identified compounds that delay the formation of tumors in mice, by targeting a key enzyme that governs how cancer cells use glucose and its metabolites.
(Science Daily) Multiple trials have shown that [breast tumor recurrence] risk decreases with age, and has prompted analysis of the benefit of radiotherapy for older patients with breast cancer. "If an older patient has been treated for breast cancer, and has a low risk of recurrence, there may be no clinical reason to subject them to radiation therapy," [radiation oncologist David E. Wazer, M.D.] said.
(Reuters) A small trial of Peregrine Pharmaceuticals Inc's experimental drug, bavituximab, showed that it doubled the length of time lung cancer patients survived, supporting the company's plans to conduct a larger study.
(Science Daily) A*STAR scientists have identified a biomarker of the most lethal form of brain tumours in adults − glioblastoma multiforme*. The scientists found that by targeting this biomarker and depleting it with a potential drug, they were able to prevent the progression and relapse of the brain tumour.
(Science Daily) [M]edicinal chemists have taken an existing drug that is being developed for use in fighting certain types of cancer, added a special structure to it, and created a more potent, efficient weapon against cancer… [Chemistry assistant professor  Mark W. Lee Jr.] and his research team used carboranes to build new drugs designed to shut off a cancer cell's energy production, which is vital for the cell's survival.
(Reuters Health) Black men needing surgery for advanced prostate cancer seem to have worse outcomes than white men, according to a new study. Based on data collected from hospitals in three states, black men who had their prostates removed were more likely to need blood transfusions, stay in the hospital longer and die while hospitalized compared to white men.
(Science Daily) Some of the body's own genetic material, known as small interfering RNA (siRNA), can be packaged then unleashed as a precise and persistent technology to guide cell behavior, researchers at Case Western Reserve University report… [T]he scientists believe that their technology could be used to starve a tumor by blocking growth of blood vessels that carry nutrition to a malignancy. Or the siRNA could bring on cancer cell death by interfering with other cellular processes.
(Science Daily)  A new molecule with anti-cancer and anti-metastatic properties has been discovered… This anticancer drug acts on cells resistant to conventional chemotherapy thanks to an entirely novel action mechanism. It targets not only the multiplication of cells but also their mobility and thus could prevent the formation of metastases. 
(Bloomberg) DNA screening offers the potential to transform medicine by predicting the risk of cancer or other severe diseases years in advance. Yet the very nature of the tests creates the potential for catastrophic error because they’re often used to make irreversible decisions, such as terminating a pregnancy or undergoing surgery to prevent cancer.
(Science Daily) A study that used a Utah genealogic database and a statewide cancer registry to examine the relationship between Parkinson disease (PD) and cancer suggests an increased risk of prostate cancer and melanoma in patients with PD and their relatives, according to a report… "Understanding this relationship could allow clinicians to provide proper assessment of cancer risk in patients with PD and might also have implications for the counseling of relatives of patients," the authors note in the study background.
(MyHealthNewsDaily) Men undergoing prostate cancer treatment commonly suffer side effects such as the growth of breast tissue or breast pain, but the breast-cancer drug tamoxifen may reduce the risk of these effects, a new review says.
(Reuters) Breast cancer cells can destroy a powerful immune response in the body and allow the disease to spread to the patient's bones, researchers in Australia reported on Monday. They also experimented with two ways to reinstate this immune response to help patients fight breast cancer, but it will take more tests and several more years for these therapies to become routine treatments, they said.
(Businessweek) A form of lung cancer that kills 400,000 people annually worldwide could be attacked by targeting newly discovered genetic mutations, according to a study that mapped the tumors’ DNA… “To our knowledge, this is the first example of a tumor that has a genomic mechanism for evading an immune response,” Matthew Meyerson, co-leader of the team that made the discovery…, said in a statement. “This provides many new therapeutic opportunities for squamous cell carcinoma that would be suitable for clinical trials.”
(Science Daily) University of Maryland researchers studied 168 patients with Stage III non-small cell lung cancer, the most common type of lung cancer, who were treated with chemotherapy and radiation over a 10-year-period, from January 2000 and December 2010. They found that 33 percent of married patients were still alive after three years compared to 10 percent of the single patients, with women faring better than men. 
(Reuters) Roche Holding AG, the world's biggest maker of cancer drugs, said it would build on its drive into personalized medicine to hold onto its long-term growth momentum and said it would keep up spending on research and development… "More than 60 percent of our pharmaceutical pipeline projects are coupled with the development of companion diagnostics in order to make treatments more effective," Chief Executive Severin Schwan said in a statement.
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