(Science Daily) A new study … outlines the specifics of how autoimmune disorders can be controlled by infusions of mesenchymal stem cells.
Mesenchymal stem cells (MSC) are highly versatile stem cells that originate from the mesoderm, or middle layer of tissue, in a developing embryo. MSC can be isolated from many different kinds of human tissue, including bone marrow and the umbilical cord.
Principal investigator Songtao Shi … said that recent studies have shown the benefits of administering MSC to patients with immune-related disorders such as graft versus host disease, systemic lupus erythematosus, rheumatoid arthritis, and more.
These studies showed that infusions of MSC appeared to quell the production and function of overactive immune cells… However, the specific mechanism behind how MSC get the immune cells under control hasn't been fully understood.
The new article shines light on how infused MSCs target and defeat overactive immune cells.
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